Real Madrid has reportedly identified Saliba as a key target in their efforts to strengthen their defense, which has struggled with injuries and age-related issues.
Saliba has been a key player for Arsenal, featuring in 48 games across all competitions and establishing himself as one of the top center-backs in the world.
He is under contract with Arsenal until 2027 and the club is interested in extending his deal further.
Arteta has spoken to Saliba about his future and is confident that the player is happy to stay with the team.
"I'm certain that he's happy here and wants to continue with us," Arteta said. "We'll take our time to negotiate his future, but I'm confident that William is committed to staying with us."